Dr Lucilla Ravà, Biostatistician, PhD , Bambino Gesù Children’s Hospital, Rome, Italy: Lucilla Ravà, PhD, is a biostatistician with a twenty years experience in this field. Graduate in 1992, she received her PhD degree in Metodological Statistics in 1998. Since 2002 she has been working in the Clinical Epidemiology Unit of BGCH. Prior working experience were in Lazzaro Spallanzani Hospital, National Institute of Health in Rome and University of Rome Tor Vergata. She teaches biostatistics to physicians an nurses at Univeristy of Rome Tor Vergata. She is involved in management and statistical analysis of hospital surveillance data, supports the development and conduction of epidemiological studies and clinical trial and provides support to hospital Departments for collecting and analyse clinical data and writing scientific paper. Worked for many national and international research projects

Degrees

Ph.D in Methodological Statistics, Sapienza Università di Rome, Italy.

B.A. in Statistical Science, Sapienza Università di Rome, Italy.

Courses Taught

Statistics

Additional Teaching Activities

• Biostatistics for Nursing Degree – University of Rome Tor Vergata” (2002 – to date)
• Biostatistics and Epidemiology at Paediatrics Specialization School, University of Rome “Tor Vergata”
• Master: “Epidemiologia delle malattie infettive in pediatria” – University of Rome “Tor Vergata”
• Resident course in Pediatrics – University of Rome “Tor Vergata”
• The mathematic model, approximation, stability and error at University Roma Tre
• Computer lab at University Roma Tre
• Statistic at University Roma Tre

Teaching Biostatistics and Epidemiology topics for several short courses:

• 3rd International Multidisciplinary Paediatric & Neonatal Acute and Critical Care Research School (IMPNACC)
• Planning of clinical trial
• How to write a scientific paper
• How to write a research protocol

Recent Publications

Manco M, Guerrera S, Ravà L, Ciofi Degli Atti M, Di Vara S, Valeri G, Vicari S. Cross-sectional investigation of insulin resistance in youths with autism spectrum disorder. Any role for reduced brain glucose metabolism? Transl Psychiatry. 2021 Apr 20;11(1):229. doi: 10.1038/s41398-021-01345-3. PMID: 33879765; PMCID: PMC8058067.

Silvetti MS, Pazzano V, Battipaglia I, Saputo FA, Mizzon C, Gimigliano F, Ammirati A, Ravà L, Drago F. Three-dimensional guided selective right ventricular septal pacing preserves ventricular systolic function and synchrony in pediatric patients. Heart Rhythm. 2021 Mar;18(3):434-442. doi: 10.1016/j.hrthm.2020.12.004. Epub 2020 Dec 8. PMID: 33307214.

Gargiulo A, Massella L, Ruggiero B, Ravà L, Ciofi Degli Atti M, Materassi M, Lugani F, Benetti E, Morello W, Molino D, Mattozzi F, Pennesi M, Maringhini S, Pasini A, Gianoglio B, Pecoraro C, Montini G, Murer L, Ghiggeri GM, Romagnani P, Vivarelli M, Emma F. Results of the PROPINE randomized controlled study suggest tapering of prednisone treatment for relapses of steroid sensitive nephrotic syndrome is not necessary in children. Kidney Int. 2021 Feb;99(2):475-483. doi: 10.1016/j.kint.2020.09.024. Epub 2020 Nov 2. PMID: 33152448.

Di Nardo M, Lonero M, Staffieri F, DI Mussi R, Murgolo F, Lorusso P, Pham T, Picardo SG, Perrotta D, Cecchetti C, RavÀ L, Grasso S. Can visual inspection of the electrical activity of the diaphragm improve the detection of patient-ventilator asynchronies by pediatric critical care physicians? Minerva Anestesiol. 2021 Mar;87(3):319-324. doi: 10.23736/S0375-9393.20.14543-7. Epub 2020 Aug 4. PMID: 32755090.

Ciofi Degli Atti ML, Campana A, Muda AO, Concato C, Ravà L, Ricotta L, Reale A, Barbieri M, D’Argenio P, Lancella L, Villani A, Raponi M. Facing SARS-CoV-2 Pandemic at a COVID-19 Regional Children’s Hospital in Italy. Pediatr Infect Dis J. 2020 Sep;39(9):e221-e225. doi 10.1097/INF.0000000000002811. PMID: 32639459. De Ioris MA, Scarselli A, Ciofi Degli Atti ML, Ravà L, Smarrazzo A, Concato C, Romani L, Scrocca R, Geremia C, Carletti M, Calò Carducci FI, Bernardi S, Coltella L, Santilli V, Chiurchiu S, Peschiaroli E, Mariani R, Marabotto C, Perrotta D, Villani A, Rossi P, D’Argenio P, Campana A, Raponi M. Dynamic Viral Severe Acute Respiratory Syndrome Coronavirus 2 RNA Shedding in Children: Preliminary Data and Clinical Consideration from a Italian Regional Center. J Pediatric Infect Dis Soc. 2020 Jul 13;9(3):366-369. doi: 10.1093/jpids/piaa065. PMID: 32444874; PMCID: PMC7543227.

De Luca D, Rava L, Nadel S, Tissieres P, Gawronski O, Perkins E, Chidini G, Tingay DG. The EPICENTRE (ESPNIC Covid pEdiatric Neonatal Registry) initiative: background and protocol for the international SARS-CoV-2 infections registry. Eur J Pediatr. 2020 Aug;179(8):1271-1278. doi: 10.1007/s00431-020-03690-9. Epub 2020 May 22. PMID: 32440887; PMCID: PMC7242019.

Silvetti MS, Muzi G, Unolt M, D’Anna C, Saputo FA, Di Mambro C, Albanese S, Ammirati A, Ravà L, Drago F. Left ventricular (LV) pacing in newborns and infants: Echo assessment of LV systolic function and synchrony at 5-year follow- up. Pacing Clin Electrophysiol. 2020 Jun;43(6):535-541. doi: 10.1111/pace.13908. Epub 2020 Apr 22. PMID: 32233121.

Bottari G, Guzzo I, Marano M, Stoppa F, Ravà L, Di Nardo M, Cecchetti C. Hemoperfusion with Cytosorb in pediatric patients with septic shock: A retrospective observational study. Int J Artif Organs. 2020 Sep;43(9):587-593. doi: 10.1177/0391398820902469. Epub 2020 Jan 31. PMID: 32003289.

Bianchi M, Alisi A, Fabrizi M, Vallone C, Ravà L, Giannico R, Vernocchi P, Signore F, Manco M. Maternal Intake of n-3 Polyunsaturated Fatty Acids During Pregnancy Is Associated With Differential Methylation Profiles in Cord Blood White Cells. Front Genet. 2019 Oct 25;10:1050. doi: 10.3389/fgene.2019.01050. PMID: 31708974; PMCID: PMC6824245.

Fagioli D, Evangelista C, Gawronski O, Tiozzo E, Broccati F, Ravà L, Dall’Oglio I, Antonielli G, Borgiani A, Cancani F, Monoscalco M, Zambrini C, Stoppa F. Correction: Pain assessment in paediatric intensive care: the Italian COMFORT behaviour scale. Nurs Child Young People. 2018 Nov 12;30(5). doi: 10.7748/ncyp.2018.e1081_crt. Erratum for: Nurs Child Young People. 2018 Sep 10;30(5):27-33. PMID: 31468800.

Fagioli D, Evangelista C, Gawronski O, Tiozzo E, Broccati F, Ravà L, Dall’Oglio I; Italian COMFORT-B Study Group. Pain assessment in paediatric intensive care: the Italian COMFORT behaviour scale. Nurs Child Young People. 2018 Sep 10;30(5):27-33. doi: 10.7748/ncyp.2018.e1081. Erratum in: Nurs Child Young People. 2018 Nov 12;30(5): PMID: 30457241.

Romiti A, Viggiano M, Conforti A, Valfré L, Ravà L, Ciofi Degli Atti M, Bagolan P, Caforio L. Ultrasonographic assessment of mediastinal shift angle (MSA) in isolated left congenital diaphragmatic hernia for the prediction of postnatal survival. J Matern Fetal Neonatal Med. 2020 Apr;33(8):1330-1335. doi: 10.1080/14767058.2018.1517329. Epub 2018 Sep 25. PMID: 30153757.

Silvetti MS, Battipaglia I, Pazzano V, Saputo FA, Ravà L, Ammirati A, Calvieri C, Ciani M, Drago F. Electroanatomic mapping-guided localization of alternative right ventricular septal pacing sites in children. Pacing Clin Electrophysiol. 2018 Sep;41(9):1204-1211. doi: 10.1111/pace.13447. Epub 2018 Aug 9. PMID: 29989185.

Cinelli G, Fabrizi M, Ravà L, Signore F, Vernocchi P, Semeraro M, Vallone C, Lanciotti R, Ciofi Degli Atti M, Manco M. Association between Maternal and Foetal Erythrocyte Fatty Acid Profiles and Birth Weight. Nutrients. 2018 Mar 23;10(4):402. doi: 10.3390/nu10040402. PMID: 29570689; PMCID: PMC5946187.

Di Paolo V, Russo I, Boldrini R, Ravà L, Pezzullo M, Benedetti MC, Galardi A, Colletti M, Rota R, Orlando D, Crocoli A, Peinado H, Milano GM, Di Giannatale A. Evaluation of Endoglin (CD105) expression in pediatric rhabdomyosarcoma. BMC Cancer. 2018 Jan 5;18(1):31. doi: 10.1186/s12885-017-3947-4. PMID: 29304781; PMCID: PMC5755407.

Chiusolo F, Fanelli V, Ciofi Degli Atti ML, Conti G, Tortora F, Pariante R, Ravà L, Grimaldi C, de Ville de Goyet J, Picardo S. CPAP by helmet for treatment of acute respiratory failure after pediatric liver transplantation. Pediatr Transplant. 2018 Feb;22(1). doi: 10.1111/petr.13088. Epub 2017 Nov 24. PMID: 29171131.

Alfieri P, Menghini D, Marotta L, De Peppo L, Ravà L, Salvaguardia F, Varuzza C, Vicari S. A comparison between linguistic skills and socio-communicative abilities in Williams syndrome. J Intellect Disabil Res. 2017 Sep;61(9):866-876. doi: 10.1111/jir.12401. Epub 2017 Jul 26. PMID: 28745018.

Silvetti MS, Ammirati A, Palmieri R, Pazzano V, Placidi S, Ravà L, Remoli R, Saputo FA, Verticelli L, Drago F. What endocardial right ventricular pacing site shows better contractility and synchrony in children and adolescents? Pacing Clin Electrophysiol. 2017 Sep;40(9):995-1003. doi: 10.1111/pace.13153. Epub 2017 Aug 26. PMID: 28744930.

Cinelli G, Fabrizi M, Ravà L, Ciofi Degli Atti M, Vernocchi P, Vallone C, Pietrantoni E, Lanciotti R, Signore F, Manco M. Influence of Maternal Obesity and Gestational Weight Gain on Maternal and Foetal Lipid Profile. Nutrients. 2016 Jun 15;8(6):368. doi: 10.3390/nu8060368. PMID: 27314385; PMCID: PMC4924209.

Nicolai R, Cortis E, Ravà L, Bracaglia C, Pardeo M, Insalaco A, Buonuomo PS, Tozzi AE, De Benedetti F. Herpes Virus Infections During Treatment With Etanercept in Juvenile Idiopathic Arthritis. J Pediatric Infect Dis Soc. 2016 Mar;5(1):76-9. doi: 10.1093/jpids/piu078. Epub 2014 Jul 31. PMID: 26908493.